WebbStatins inhibit an enzyme called HMG-CoA reductase …. so they’re known as HMG-CoA reductase inhibitors ( hydroxymethylglutaryl – coenzyme A reductase). HMG-CoA … WebbGeneric Name: simvastatin Trade Name(s): Zocor. Drug Classification: Therapeutic: lipid-lowering agents Pharmacologic: HMG-CoA reductase in-hibitors (statin)Therapeutic …
Assessment report - European Medicines Agency
Webb19 feb. 2024 · Additionally, simvastatin dosed 2 hours before, and 4 and 10 hours after roxadustat in 28 (CL-0541) healthy subjects, resulted in increases of C max and AUC inf … Webb4 aug. 2024 · liver problems - nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). … how to start my business without money
Simvastatin Sandoz - FASS Allmänhet
Availability. 5 mg, 10 mg, 20 mg, 40 mg, 80 mg tablets. Actions. Inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase; similar in action to lovastatin but more potent. HMG-CoA reductase inhibitors increase HDL cholesterol, and decrease LDL cholesterol, and total cholesterol synthesis. … Visa mer Inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase; similar in action to lovastatin but more potent. HMG-CoA reductase inhibitors increase HDL cholesterol, and decrease LDL cholesterol, and total … Visa mer Homozygous familial hypercholesterolemia, history of liver disease, alcoholics. Safety and effectiveness in children and adolescents are not established. Visa mer Indicated by decreased serum triglycerides, decreased LDL, cholesterol, and modest increases in HDL cholesterol. Visa mer Hypercholesterolemia (alone or in combination with bile acid sequestrants), familial hypercholesterolemia. Reduces risk of coronary death … Visa mer WebbSimvastatin er er substrat for BCRP og samtidig behandling med midler, som hæmmer BCRP kan øge koncentrationen. For visse af midlerne bør dosis af simvastatin ikke … WebbAdministration Oral Give as a single dose, preferably 1 h before or 2 h after breakfast, to prevent insomnia. meals. Maintenance dosage for older adults may be 25% lower than … react ip