Keratin 5 cre

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August undefined, 2024

Web1 jan. 2007 · The keratin 5‐Cre recombinase (K5Cre) transgenic mouse line has been used to generate skin specific gene deletions. We found that the K5Cre mice display a unique … Web029155 B6N.129S6(Cg)- Krt5 tm1.1(cre/ERT2)Blh /J Krt5-CreERT2 knock-in mice have both endogenous gene and tamoxifen-inducible Cre recombinase expression directed to …

Keratin 15 Promoter Targets Putative Epithelial Stem Cells …

http://www.informatics.jax.org/allele/MGI:1926815 Webspecific knockout of Esr1 driven by keratin 5-Cre (K5-Esr1KO). We show here that loss of epithelial ESR1 in the vagina resulted in aberrant epithelial cell proliferation in the suprabasal cell layers and led to failure of keratinized differentiation. Gene expression analysisshowed thatseveral knownestrogentarget genes,includ- mary ann brown mosheim

281268 - Gene ResultKRT5 keratin 5 [ (cattle)]

Web29 sep. 2006 · The keratin 5-Cre recombinase (K5Cre) transgenic mouse line has been used to generate skin specific gene deletions. We found that the K5Cre mice display a unique phenotype when bred to homozygosity. The K5Cre +/+ mice have a wavy hair coat and curly whiskers. WebHere we analyzed keratinocytes of the female K5-Cre: Pig-a flox/+ mice with heterozygous knockout of Pig-a. These cells exhibited the mosaic pattern of GPI-anchor positive and … Web11 okt. 2024 · Krt5-cre 最近也用来研究Basal-like 型乳腺癌。目前主要用来研究乳腺癌的cre 工具鼠如下：小鼠名称原始文献引用文献数 Krt5tm1.1 (cre/ERT2)Blh (Van … mary ann brunhuber

018394 - K5-Cre-ER[T2] Strain Details - The Jackson …

Keratins as the main component for the mechanical integrity of

WebA 14-kb fragment of human K5 promoter used to control the expression of Cre transgene and the nuclear localizing signal was added at 5 of Cre gene. from publication: ... WebFor example, tamoxifen-induced deletion of the gene encoding Stat-3 specifically in keratinocytes (under the control of the keratin 5 promoter) resulted in reduced inflammation compared to wild-type animals upon their treatment with imiquimod. 3 In contrast, transgenic mouse models in which Stat-3 was knocked out in T cells by Cre recombinase under the … huntington national bank corporate addressWebA keratin 5-Cre-driven epidermis-specific Ncstn conditional knockout mutant was generated and it was determined that this mutant recapitulated the major phenotypes of AI, … mary ann bruce

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Keratin 5 cre

KRT5 Gene - GeneCards K2C5 Protein K2C5 Antibody

Web28 jan. 2024 · Subsequent studies using conditional Piga inactivation with keratin 5-Cre (K5Cre), expressed in basal cells of the skin, revealed lethality within a few days of birth due to abnormal skin development , reinforcing the importance of … WebKeratin 5-Cre-driven deletion of Ncstn in an acne inversa-like mouse model leads to a markedly increased IL-36a and Sprr2 expression: Jun Yang 1, Lianqing Wang 1, 2, Yingzhi Huang 1, Keqiang Liu 1, Chaoxia Lu 1, Nuo Si 1, Rongrong Wang 1, Yaping Liu 1 (), Xue Zhang 1 (): 1.McKusick-Zhang Center for Genetic Medicine, State Key Laboratory of …

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WebKeratin 14 is a member of the type I keratin family of intermediate filament proteins. Keratin 14 was the first type I keratin sequence determined. Keratin 14 is also known … WebView mouse Krt5 Chr15:101615505-101621333 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression

Web10 jan. 2024 · Unlike its family member p53, TP63 is rarely mutated in human cancer. However, Delta Np63 alpha protein levels are often elevated in tumors of epithelial origin, … WebThe keratin 5-Cre recombinase (K5Cre) transgenic mouse line has been used to generate skin specific gene deletions. We found that the K5Cre mice display a unique phenotype …

Web018394 - K5-Cre-ER [T2] Strain Details. Technical Information Scientists. Overview. How it's Used. Web2 jun. 2024 · Abstract. In the urinary bladder, the normal urothelium is divided into three subpopulations of cells: superficial umbrella cells, intermediate cells, and a basal layer, …

Web23 jul. 2024 · These observations were reiterated in the skin of keratin 5-Cre-targeted ΔNp63α transgenic mice, which display a hyperproliferative epidermis with suprabasal expression of ΔNp63α and corresponding enhanced nuclear localization of c-Rel, as well as an inflammatory dermal infiltrate of lymphoid and myeloid lineages [136,137,138].

WebIn this study, we generated a keratin 5-Cre-driven epidermis-specific Ncstn conditional knockout mutant in mice. We determined that this mutant recapitulated the major … mary ann brunoWebClaresa Extend Care 5in1 Keratin #5 – 5ml.. Het creëren van gladde en verzorgde nagels gaat sneller en gemakkelijker dan ooit. Met de innovatieve... mary ann bruno obituaryWeb1 okt. 2013 · These results furthermore demonstrate that K5-Cre gene constructs, previously reported to be activated starting at approximately E12.5 in the forming … huntington national bank cortland ohioWebAbstract. Three mouse lines expressing Cre recombinase under the control of the human K14 promoter induced specific deletion of loxP flanked target sequences in the … maryann brown plainville maWebTransgene. description. Transgene Type: Transgenic (Recombinase) Mutation: Insertion. Mutation details : A 14kb fragment of human keratin 5 (KRT5) promoter was used to … huntington national bank customer careWebProduction Details. Krt5-Cre;Braf f/f ;Raf1 f/f mice were generated by crossing Krt5-Cre;Braf f/f with Krt5-Cre;Raf1 f/f animals. Conditional. Yes. Conditional Description. Tissue … maryann bruce obituaryWeb2 sep. 2024 · The Runt-related transcription factor (Runx) family has been suggested to play roles in stem cell regulation, tissue development, and oncogenesis in various tissues/organs. In this study, we investigated the possible functions of Runx1 and Runx3 in keratinocyte differentiation. Both Runx1 and Runx3 proteins were detected in primary cultures of … mary ann brunson obituary