WebSep 11, 2013 · Patients with obstructive lung diseases display abnormal circadian rhythms in lung function. We determined the mechanism whereby environmental tobacco/cigarette smoke (CS) modulates expression of the core clock gene BMAL1, through Sirtuin1 (SIRT1) deacetylase during lung inflammatory and injurious responses. WebDec 15, 2009 · Circadian oscillations are statistically significant as analyzed with CircWave (TNF-α and IL-6: P < 0.05). ... profiles were determined by using GeneChip Mouse Gene …
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WebMay 18, 2016 · Unpaired Student's t test was used for all other data analysis. Circadian rhythmicity in individual gene expression profiles was detected using a harmonic regression analysis (CircWave 1.4 software generated by Dr. Roelof Hut; www.euclock.org). The program produces a Fourier curve that describes the data by adding as many harmonics … birthday cakes delivered gluten free
Functional analysis of Pdp1 and vrille in the circadian system of a ...
WebApr 11, 2014 · Originally developed for the analysis of short and sparse data series, the extended cosinor has been further developed for the analysis of long time series, focusing both on rhythm detection and parameter estimation. Attention is given to the assumptions underlying the use of the cosinor and ways to determine whether they are satisfied. WebThe laboratory was established in 1986 and has the mission of conducting experimental research on circadian rhythms. Other activities include research in thermal physiology, development of data analysis procedures, discussion of academic issues, and design of computer software for scientific research and higher education. Lab History WebDec 10, 2024 · CircWave analysis indicated the absence of circadian rhythmicity in the expression patterns of all clock genes tested in Pitx3ak mice but not in control animals ( Figures 2 A–2F). Confirming these results, one-way ANOVA indicated the absence of time-dependent changes in all clock genes tested in Pitx3ak mice ( Table S1 ). birthday cakes delivery india